SYNSEN

Modeling the effects of microplastic ingestion on cellular aging and neurodegenerative diseases

THE PROJECT SYNSEN

CONTEXT AND MAIN ISSUES

Plasticosis is the first disease directly linked to the ingestion of plastic particles, highlighted in seabirds by the MicroPOW project, supported by Pure Ocean since 2021.

It consists in the deregulation of cellular tissue repair mechanisms, leading to uncontrolled cell proliferation: a form of cancer. This disease highlights the threats posed by plastic pollution to human and environmental health, underlining the need for action to reduce the impact of plastic waste on marine ecosystems.

GOALS

Characterize the consequences of plasticosis, a disease linked to the ingestion of microplastics, on the DNA of seabirds.

METHOD

The SynSen project uses a multidisciplinary approach, combining molecular biology and neuroscience techniques, to study the effects of microplastics on seabird DNA and cellular aging processes.

In particular, researchers will explore the interactions between microplastics and telomeres: regions of DNA involved in regulating cell growth, aging and senescence.

HOW IS THIS PROJECT INNOVATIVE?

Synsen stands out for its exploration of the links between exposure to microplastics and neurodegenerative diseases in seabirds. By combining ecotoxicology research with environmental health, this project sheds light on the risks to marine wildlife and human health.

Pure Ocean supports Synsen’s innovative approach to understanding and mitigating the impact of plastic pollution on marine ecosystems and human health.